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WHAT IS CARBOXYTHERAPY

CARBON DIOXIDE
AS A THERAPEUTIC
SIGNAL.


Carboxytherapy is the therapeutic use of carbon dioxide (CO₂) to support local circulation and oxygen delivery in skin and underlying tissue.

The delivery methods differ. The foundational physiologic concept remains the same.

TRADITIONAL CARBOXYTHERAPY

Traditional carboxytherapy introduces purified CO₂ through small injections beneath the skin.

TRADITIONAL CARBOXYTHERAPY

A self-generating gel produces CO₂ and maintains contact with the treatment area in a non-invasive, device-free format.

FROM THERAPEUTIC WATERS TO TOPICAL DELIVERY.

1400's

Japan

Japanese Samurai warriors were believed to use naturally carbonated hot springs to support wound healing and recovery after battle, an early example of the therapeutic use of carbon dioxide-rich waters.

1400s

The spa era

Naturally carbonated mineral springs were prized for their apparent healing effects. The first documented, deliberate therapeutic use of purified carbon dioxide is traced to a German spa in the early 1700s.

1932

Royat, France

At the famous thermal springs of Royat, physicians moved beyond bathing and used carbon dioxide injections directly to treat poor circulation and slow-healing wounds , widely considered the birthplace of modern carboxytherapy.

Mid-1900s

A research home

A dedicated research institute in Royat helped formalize the practice, producing decades of clinical study and spreading the technique across Europe and, later, South America.

1995

The treatment gets its name

The term "carboxytherapy" was formally introduced to the medical community at an aesthetic-medicine assembly in Rome, giving the century-old practice a single, recognizable name.

Early 2000s

Arrival in the United States

As it gained popularity in Europe and Brazil where dedicated clinics became commonplace, it crossed into the U.S. aesthetic scene. Certain CO₂ delivery devices received U.S. regulatory clearance in this period.

Today

A non-invasive evolution

Topical carboxytherapy gel has extended the treatment beyond the clinic, making CO₂-based tissue support available for everyday skin health and gentle, needle-free recovery.

THE BOHR EFFECT

CO₂ HELPS SIGNAL OXYGEN RELEASE WHERE IT IS NEEDED.

When local CO₂ concentration increases, hemoglobin’s affinity for oxygen
decreases, facilitating oxygen release into surrounding tissue.

1. Introduce CO₂

A treatment delivers a burst of carbon dioxide to the skin. Think of red blood cells as delivery trucks carrying oxygen, they need a signal for where to drop it off.

2. The body responds

Wherever CO₂ is high, the body assumes that tissue is working hard and needs oxygen. Small blood vessels widen and circulation opens up toward the area.

3. Oxygen arrives

Fresh, oxygen-rich blood floods in bringing nutrients and carrying waste away using nothing but your body's own delivery system.

WHY TOPICAL CARBOXYTHERAPY NOW

YOUR SKINCARE ROUTINE IS EVOLVING. YOUR SKIN DESERVES MORE.

Today’s skincare goes beyond what you put on the surface. Topical carboxytherapy brings CO₂ technology into a simple, non-invasive face mask experience designed to support refreshed, hydrated, healthier-looking skin.

With no needles and no device required, it’s an easy addition to your skincare routine when your skin needs a little extra care, whether you’re looking to revive tired-looking skin, boost hydration, or support a fresh, healthy-looking glow.

Advanced skincare technology, made simple.

THE CO2LIFT® ECOSYSTEM

Carboxytherapy for every need - professional treatments, at-home care, and intimate health. Different solutions. The same science.

GLO By CO2Lift® - Daily skin
revitalization at home.
Shop GLO >
CO2Lift® PRO - Trusted by
providers worldwide.
Learn About PRO >
CO2Lift® V - Intimate health,
real solutions.
Shop V >

CARBOXYTHERAPY, MADE FOR YOUR SKIN.

Bring the science of CO₂ carboxytherapy into your skincare routine with a non-invasive treatment designed to refresh, hydrate, and support healthier-looking skin.